Severe rhabdomyolysis and Guillain-Barré syndrome in an unimmunized adult with measles virus infection: a case report

Measles cases in Europe have been exponentially increasing in recent years, exposing a growing number of unimmunized individuals to severe and/or uncommon disease manifestations. We hereby describe a unique case of an unvaccinated adult with measles virus infection who developed the rare co-occurrence of severe rhabdomyolysis and Guillain-Barré syndrome. The patient also had transaminitis and profound thrombocytopenia, and fully recovered after supportive treatment and intravenous immunoglobulin therapy, with no chronic sequelae. This case highlights the need for increased clinical awareness and close laboratory and neurological monitoring in adult patients with measles.

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Publication Details

Journal
Heliyon
Published
2026-04-01
DOI
https://doi.org/10.1016/j.heliyon.2026.e44907
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
Field-Weighted Citation Impact
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Severe rhabdomyolysis and Guillain-Barré syndrome in an unimmunized adult with measles virus infection: a case report

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Severe rhabdomyolysis and Guillain-Barré syndrome in an unimmunized adult with measles virus infection: a case report

Maria Rosaria Cuomo, Antonio Falletta, Cristiana Leanza, Vito Trinchieri, A. Destro, Elena Casali, Francesco Eugenio Romani, Guido Siccardi, R Donà, Julieta Morcos, Vera Mauro, Claudia D'Agostino, Claudio Maria Mastroianni
article en

Abstract

Measles cases in Europe have been exponentially increasing in recent years, exposing a growing number of unimmunized individuals to severe and/or uncommon disease manifestations. We hereby describe a unique case of an unvaccinated adult with measles virus infection who developed the rare co-occurrence of severe rhabdomyolysis and Guillain-Barré syndrome. The patient also had transaminitis and profound thrombocytopenia, and fully recovered after supportive treatment and intravenous immunoglobulin therapy, with no chronic sequelae. This case highlights the need for increased clinical awareness and close laboratory and neurological monitoring in adult patients with measles.

HeliyonVol. 12(7)
Openalex Percentile: Top 25%
Peripheral Neuropathies and Disorders
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