From clinics to sewers: leveraging environmental surveillance and whole genome sequencing to inform transmission of ESBL- <i>Escherichia coli</i> in Switzerland
which overlaps with circulating clinically relevant strains. IMPORTANCE: isolates across sectors using whole genome sequencing, providing an opportunity to understand exchange of bacterial isolates between clinics, communities, livestock, and wildlife.
Authors
- Louis du Plessis (ORCID: https://orcid.org/0000-0003-0352-6289)
- Sheena Conforti (ORCID: https://orcid.org/0000-0002-0173-6170)
- Alexia Cusini
- Claudia Bagutti (ORCID: https://orcid.org/0000-0002-1968-5965)
- Jon Paulin Zumthor
- Oliver Nolte (ORCID: https://orcid.org/0000-0002-1761-0812)
- Timothy R. Julian (ORCID: https://orcid.org/0000-0003-1000-0306)
- G. Greub
- Silvio D. Brugger (ORCID: https://orcid.org/0000-0001-9492-9088)
- Salomé N. Seiffert (ORCID: https://orcid.org/0000-0003-1639-131X)
- Jana S. Huisman (ORCID: https://orcid.org/0000-0002-1782-8109)
- Tanja Stadler (ORCID: https://orcid.org/0000-0001-6431-535X)
- C. Kocher (ORCID: https://orcid.org/0009-0002-8909-0657)
- Karoline Leuzinger (ORCID: https://orcid.org/0000-0002-5654-9356)
- Roger D. Kouyos (ORCID: https://orcid.org/0000-0002-9220-8348)
- Carola Maffioli
- Alban Ramette (ORCID: https://orcid.org/0000-0002-3437-4639)
- Valeria Gaia (ORCID: https://orcid.org/0009-0000-6564-3099)
- Mara Neacsu
- J. Becker
- Sarah Tschudin-Sutter
- Adrian Egli
Institutions
- University of Bern (CH)
- SIB Swiss Institute of Bioinformatics (CH)
- University of Zurich (CH)
- University Hospital of Basel (CH)
- ETH Zurich (CH)
- State Archives Basel-Stadt (CH)
- Hospital Base (CL)
- Ente Ospedaliero Cantonale (CH)
- University Hospital of Zurich (CH)
- Cangzhou Central Hospital (CN)
- Center for Human Genetics (US)
- Cantonal Archives of the Grisons (CH)
- Labormedizinische Zentrum Dr Risch (Switzerland) (CH)
- Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit (DE)
- Swiss Federal Institute of Aquatic Science and Technology (CH)
- Massachusetts Institute of Technology (US)
- University of Lausanne (CH)
Publication Details
- Journal
- Applied and Environmental Microbiology
- Published
- 2026-04-06
- DOI
- https://doi.org/10.1128/aem.01848-25
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Bundesamt für Gesundheit