Exploring Gallium(III) Complexes as Emerging Therapeutic Candidates for Breast Cancer
displayed high hydrolytic stability, selective tumor-cell uptake, cytoplasmic localization, and significant tumor growth inhibition in zebrafish xenografts without observable systemic toxicity in mice, underscoring the potential of the heteroscorpionate platform.
Authors
- Marc Martínez de Sarasa Buchaca (ORCID: https://orcid.org/0000-0002-8719-1895)
- Julio Escribano (ORCID: https://orcid.org/0000-0002-8919-8134)
- Carmen Moya
- Sofia W. Giron Blas
- Santiago García-Yuste
- María del Mar Noblejas-López
- Fernando de Andrés
- Iván Bravo
- Agustín Lara-Sánchez
- Carlos Alonso-Moreno
- Pablo Salcedo-Abraira
- Antonio Rodríguez-Diéguez
- Alberto Moreno-Fernández
- Jesús-José Ferre-Fernández
- Jose-Daniel Aroca-Aguilar
- Elena Domínguez-Jurado
Institutions
- University of Alicante (ES)
- Universidad de Granada (ES)
- Instituto de Información Científica y Tecnológica (CU)
- Instituto de Química Orgánica General (ES)
- Centro Uruguayo de Imagenología Molecular (UY)
- University of Castilla-La Mancha (ES)
Publication Details
- Journal
- Journal of Medicinal Chemistry
- Published
- 2026-04-06
- DOI
- https://doi.org/10.1021/acs.jmedchem.5c03480
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministerio de Ciencia, Innovación y Universidades
- Universidad de Castilla-La Mancha
- Junta de Comunidades de Castilla-La Mancha
- European Regional Development Fund