Uncoupling Relapse Reduction and Disability Progression

The aim of this study was to evaluate whether the treatment effects of tolebrutinib on confirmed disability worsening (CDW) diverge from its effects on relapse prevention compared with other disease-modifying therapies (DMTs) for relapsing multiple sclerosis (MS).

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Publication Details

Journal
Neurology Clinical Practice
Published
2026-04-06
DOI
https://doi.org/10.1212/cpj.0000000000200612
Primary Topic
Lower Extremity Biomechanics and Pathologies
Type
article
Field-Weighted Citation Impact
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article

Uncoupling Relapse Reduction and Disability Progression

Alessio Signori, Noemi Montobbio, Irene Schiavetti, Alessandra Krenn et al.
Neurology Clinical Practice
Lower Extremity Biomechanics and Pathologies
article

Uncoupling Relapse Reduction and Disability Progression

Alessio Signori, Noemi Montobbio, Irene Schiavetti, Alessandra Krenn, Francesca Bovis, Maria Pia Sormani, Marta Ponzano
article en

Abstract

The aim of this study was to evaluate whether the treatment effects of tolebrutinib on confirmed disability worsening (CDW) diverge from its effects on relapse prevention compared with other disease-modifying therapies (DMTs) for relapsing multiple sclerosis (MS).

Neurology Clinical PracticeVol. 16(3)
Ospedale Policlinico San Martino (IT), University of Genoa (IT)
Openalex Percentile: Top 23%
Lower Extremity Biomechanics and Pathologies
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