Distinct principles of genome compartmentalization in <i>Drosophila</i> and humans revealed by osmotic stress

through a mechanism distinct from the heterochromatin-driven B compartment interactions that predominate in vertebrates, revealing fundamentally different organizational principles between fly and human genomes.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-04-06
DOI
https://doi.org/10.64898/2026.04.02.716189
Primary Topic
Genomics and Chromatin Dynamics
Type
article
Field-Weighted Citation Impact
0.00
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article

Distinct principles of genome compartmentalization in Drosophila and humans revealed by osmotic stress

Rachel Patton McCord, Bright Amankwaa, Jacob T. Sanders, Tianchun Xue et al.
bioRxiv (Cold Spring Harbor Laboratory)
Genomics and Chromatin Dynamics
article

Distinct principles of genome compartmentalization in Drosophila and humans revealed by osmotic stress

Rachel Patton McCord, Bright Amankwaa, Jacob T. Sanders, Tianchun Xue, Mariano Labrador, Christopher Playter, Emily C. Stow
article en

Abstract

through a mechanism distinct from the heterochromatin-driven B compartment interactions that predominate in vertebrates, revealing fundamentally different organizational principles between fly and human genomes.

bioRxiv (Cold Spring Harbor Laboratory)
University of Tennessee at Knoxville (US)
Life in Land
Openalex Percentile: Top 28%
Genomics and Chromatin Dynamics
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