Post-POEM Esophageal Leak Successfully Managed With Endoscopic Vacuum Therapy

Esophageal leak is a well-described complication of endoscopic peroral endoscopic myotomy (POEM). Although various endoscopic techniques exist for managing mucosal defects, their efficacy is not universal, and successful closure is not guaranteed. The endoscopic vacuum therapy (EVT, EndoVAC) has been implemented in the management of mucosal defects. We hereby present a 46-year-old man who developed a persistent esophageal leak after POEM, which was successfully managed with the EndoVAC following multiple unsuccessful closure attempts using conventional methods.