Comparative Analysis of the Predictive Utility of Gastric Mucosal PH and Lactate in Septic Shock

< 0.001), indicating that combined assessment markedly improves prognostic accuracy in septic shock.ConclusionBoth gastric mucosal pH and blood lactate levels were associated with in-hospital mortality in patients with septic shock. While lactate did not achieve statistical significance as an independent predictor in the current model, PHi demonstrated an independent connection with prognosis in the multivariable analysis. These results imply that gastric mucosal pH may provide a potential regional perfusion viewpoint for evaluating the state, in contrast to lactate, which represents systemic metabolic status. Significantly, predictive accuracy increased when both markers were evaluated together, suggesting that systemic and regional indicators can be complementing in risk assessment.

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Publication Details

Journal
Journal of Intensive Care Medicine
Published
2026-04-06
DOI
https://doi.org/10.1177/08850666261434931
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
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article

Comparative Analysis of the Predictive Utility of Gastric Mucosal PH and Lactate in Septic Shock

Zhai Jianhua, Tang Sha, Zhang Yining
Journal of Intensive Care Medicine
Sepsis Diagnosis and Treatment
article

Comparative Analysis of the Predictive Utility of Gastric Mucosal PH and Lactate in Septic Shock

Zhai Jianhua, Tang Sha, Zhang Yining
article en

Abstract

< 0.001), indicating that combined assessment markedly improves prognostic accuracy in septic shock.ConclusionBoth gastric mucosal pH and blood lactate levels were associated with in-hospital mortality in patients with septic shock. While lactate did not achieve statistical significance as an independent predictor in the current model, PHi demonstrated an independent connection with prognosis in the multivariable analysis. These results imply that gastric mucosal pH may provide a potential regional perfusion viewpoint for evaluating the state, in contrast to lactate, which represents systemic metabolic status. Significantly, predictive accuracy increased when both markers were evaluated together, suggesting that systemic and regional indicators can be complementing in risk assessment.

Journal of Intensive Care Medicine
Tianjin Medical University General Hospital (CN), Tianjin Medical University (CN)
Good health and well-being
Openalex Percentile: Top 23%
Sepsis Diagnosis and Treatment
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Comparative Analysis of the Predictive Utility of Gastric Mucosal PH and Lactate in Septic Shock — Zhai Jianhua, Tang Sha, et al. · Journal of Intensive Care Medicine (2026) | TGRS Research Map | TGRS