Metal Modulation of Oxytocin Structure, Function, and Receptor Interactions

, and other metals influence oxytocin's conformational landscape and receptor interactions through distinct coordination modes. We highlight emerging applications in biosensor development and therapeutic formulation that leverage these metal-binding properties. Advancing our understanding of metal-mediated modulation of oxytocin function will enhance our knowledge of peptide hormone regulation and provide new avenues for therapeutic intervention in conditions involving dysregulated oxytocin signaling.

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Publication Details

Journal
European Journal of Inorganic Chemistry
Published
2026-04-06
DOI
https://doi.org/10.1002/ejic.202500462
Primary Topic
Neuroendocrine regulation and behavior
Type
article
Field-Weighted Citation Impact
0.00

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article

Metal Modulation of Oxytocin Structure, Function, and Receptor Interactions

Marie C. Heffern
European Journal of Inorganic Chemistry
Neuroendocrine regulation and behavior
article

Metal Modulation of Oxytocin Structure, Function, and Receptor Interactions

Marie C. Heffern
article en

Abstract

, and other metals influence oxytocin's conformational landscape and receptor interactions through distinct coordination modes. We highlight emerging applications in biosensor development and therapeutic formulation that leverage these metal-binding properties. Advancing our understanding of metal-mediated modulation of oxytocin function will enhance our knowledge of peptide hormone regulation and provide new avenues for therapeutic intervention in conditions involving dysregulated oxytocin signaling.

European Journal of Inorganic Chemistry
University of California, Davis (US)
National Institutes of Health
Openalex Percentile: Top 31%
Neuroendocrine regulation and behavior
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