Long-term recurrence-free survival following total penectomy and additional chemotherapy for solitary penile metastasis from muscle invasive bladder cancer

Penile metastasis from bladder cancer is extremely rare and often presents as part of multiple distant metastases. However, no established standard treatment exists for a solitary penile metastasis. We report an 83-year-old male diagnosed with a solitary penile metastasis two years after radical cystectomy for muscle-invasive bladder cancer. Histopathological examination revealed a solitary tumor within the corpus cavernosum consistent with metastatic urothelial carcinoma. The patient underwent total penectomy followed by adjuvant chemotherapy and has remained recurrence-free for seven years. This case illustrates the potential effectiveness of combining radical surgery and chemotherapy in managing a rare penile metastasis from bladder cancer.