Potential of oral combination lipid‑lowering therapy beyond statins: a simulation‑based perspective from the SANTORINI study
Sequential theoretical addition of ezetimibe and bempedoic acid increased LDL‑C goal achievement and was associated with modeled reductions in MACE. Risk estimates were inferred from LDL‑C lowering in the simulation.
Authors
- Raul D. Santos
Institutions
- Universidade de São Paulo (BR)
- Hospital Israelita Albert Einstein (BR)
- Hospital São Paulo (BR)
Publication Details
- Journal
- American Journal of Preventive Cardiology
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1016/j.ajpc.2026.101596
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico