Risk factors for atypical femur fractures with and without bisphosphonate treatment: a national nested case-control study

< .01); however, other geometric differences were minor and did not support the hypothesis. The absence of identifiable mechanisms for stress fracture formation suggests that future research should test factors not captured in registry data or femoral geometry. Possibly, physical activity levels or subtle bone metabolic conditions may be contributing to the pathogenesis of AFF, particularly in BP-naïve individuals.

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Publication Details

Journal
JBMR Plus
Published
2026-04-01
DOI
https://doi.org/10.1093/jbmrpl/ziag059
Primary Topic
Bone health and osteoporosis research
Type
article
Field-Weighted Citation Impact
0.00

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article

Risk factors for atypical femur fractures with and without bisphosphonate treatment: a national nested case-control study

Hans Peter Bögl, Georg Zdolsek, Daphne Wezenberg, Johan Lyth et al.
JBMR Plus
Bone health and osteoporosis research
article

Risk factors for atypical femur fractures with and without bisphosphonate treatment: a national nested case-control study

Hans Peter Bögl, Georg Zdolsek, Daphne Wezenberg, Johan Lyth, Jörg Schilcher, Karl Michaëlsson, Rickard Sand, Rasmus Mikiver
article en

Abstract

< .01); however, other geometric differences were minor and did not support the hypothesis. The absence of identifiable mechanisms for stress fracture formation suggests that future research should test factors not captured in registry data or femoral geometry. Possibly, physical activity levels or subtle bone metabolic conditions may be contributing to the pathogenesis of AFF, particularly in BP-naïve individuals.

JBMR PlusVol. 10(6)
Linköping University (SE), Uppsala University (SE), University of Gävle (SE), Gävle Hospital (SE), Linköping University Hospital (SE), Centre for Research and Development (ZW)
Svenska Forskningsrådet Formas, Knut och Alice Wallenbergs Stiftelse
Good health and well-being
Openalex Percentile: Top 35%
Bone health and osteoporosis research
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