Utility of guide catheter extension and intravascular ultrasound to facilitate transcatheter device closure of aortic paravalvular leak

Paravalvular leak (PVL) refers to the retrograde flow of blood through a channel between an implanted valve prosthesis and native cardiac tissue, due to the absence of an appropriate seal. Most PVLs are haemodynamically non-significant; however, large leaks can present with symptoms of heart failure and/or haemolysis, with impact on quality of life. In many patients, re-operation is associated with high risk and alternative treatments using transcatheter closure techniques have been applied. We present the case of a septuagenarian male who underwent aortic PVL closure facilitated by use of a guide catheter extension and intravascular ultrasound. This report illustrates that these adjunctive techniques, more commonly used in coronary angioplasty procedures, can be used to enable complex PVL closure.

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Publication Details

Journal
BMJ Case Reports
Published
2026-04-01
DOI
https://doi.org/10.1136/bcr-2025-269663
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
Field-Weighted Citation Impact
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article

Utility of guide catheter extension and intravascular ultrasound to facilitate transcatheter device closure of aortic paravalvular leak

William Smith, Beth Brailsford, Thomas Andrew Kite
BMJ Case Reports
Cardiac Valve Diseases and Treatments
article

Utility of guide catheter extension and intravascular ultrasound to facilitate transcatheter device closure of aortic paravalvular leak

William Smith, Beth Brailsford, Thomas Andrew Kite
article en

Abstract

Paravalvular leak (PVL) refers to the retrograde flow of blood through a channel between an implanted valve prosthesis and native cardiac tissue, due to the absence of an appropriate seal. Most PVLs are haemodynamically non-significant; however, large leaks can present with symptoms of heart failure and/or haemolysis, with impact on quality of life. In many patients, re-operation is associated with high risk and alternative treatments using transcatheter closure techniques have been applied. We present the case of a septuagenarian male who underwent aortic PVL closure facilitated by use of a guide catheter extension and intravascular ultrasound. This report illustrates that these adjunctive techniques, more commonly used in coronary angioplasty procedures, can be used to enable complex PVL closure.

BMJ Case ReportsVol. 19(4)
Nottingham University Hospitals NHS Trust (GB), Chesterfield Royal Hospital NHS Foundation Trust (GB)
Openalex Percentile: Top 23%
Cardiac Valve Diseases and Treatments
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