Causal Inference in Health Disparities Research

Causal inference is a central endeavor in health disparities research. For decades, it has been used to both measure and explain disparity and discrimination and to evaluate the impact of interventions on disparity and discrimination. This article reviews the use of causal inference methods for each of these endeavors, highlighting critical challenges that emerging work attempts to overcome. A key feature of a newer proposal is to use a descriptive measure of disparity that builds in normative and ethical assumptions and then to perform causal inference on that measure of disparity when seeking to inform and evaluate interventions. In this way, the measure of disparity is applicable to real-world data; is consistent across measurement, intervention development, and evaluation efforts; and builds in normative and ethical assumptions that promote transparency, dialogue, debate, and reproducibility. The article also briefly highlights causal inference methods for transformative interventions.

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Publication Details

Journal
Annual Review of Public Health
Published
2026-04-02
DOI
https://doi.org/10.1146/annurev-publhealth-071123-032637
Primary Topic
Cultural Competency in Health Care
Type
article
Field-Weighted Citation Impact
0.00

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article

Causal Inference in Health Disparities Research

John Wyse Jackson
Annual Review of Public Health
Cultural Competency in Health Care
article

Causal Inference in Health Disparities Research

John Wyse Jackson
article en

Abstract

Causal inference is a central endeavor in health disparities research. For decades, it has been used to both measure and explain disparity and discrimination and to evaluate the impact of interventions on disparity and discrimination. This article reviews the use of causal inference methods for each of these endeavors, highlighting critical challenges that emerging work attempts to overcome. A key feature of a newer proposal is to use a descriptive measure of disparity that builds in normative and ethical assumptions and then to perform causal inference on that measure of disparity when seeking to inform and evaluate interventions. In this way, the measure of disparity is applicable to real-world data; is consistent across measurement, intervention development, and evaluation efforts; and builds in normative and ethical assumptions that promote transparency, dialogue, debate, and reproducibility. The article also briefly highlights causal inference methods for transformative interventions.

Annual Review of Public HealthVol. 47(1)
Johns Hopkins University (US), Johns Hopkins Medicine (US), Johns Hopkins Center for Health Security (US)
National Institutes of Health, National Heart, Lung, and Blood Institute, NIH Office of the Director
Gender equality
Openalex Percentile: Top 27%
Cultural Competency in Health Care
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Causal Inference in Health Disparities Research — John Wyse Jackson · Annual Review of Public Health (2026) | TGRS Research Map | TGRS