Atypical skin involvement as a harbinger of small-cell lung cancer
A male in his late fifties, a chronic smoker, presented to his primary care physician with multiple painless subcutaneous swellings over the torso, which were misdiagnosed as a cutaneous infection for more than a month. Later, he developed haemoptysis for which he presented to our tertiary care subspecialty unit. Further evaluation with imaging revealed a left lung mass with adrenal and gastric lesions, raising suspicion of a lung malignancy with metastasis. A biopsy from a chest wall swelling confirmed primary lung small cell carcinoma with positive synaptophysin expression. Despite timely whole-brain radiotherapy and chemotherapy, his condition deteriorated rapidly, and he succumbed within weeks. This case highlights the rare presentation of small-cell lung carcinoma with cutaneous metastases, which is associated with poor prognosis.
Authors
- Gayathri Saravanan
- Lokesh Saini (ORCID: https://orcid.org/0000-0003-3153-0736)
- Ravi Hari Phulware (ORCID: https://orcid.org/0000-0002-5136-7254)
- Anjana Anilkumar
Institutions
- Seema Dental College and Hospital (IN)
- All India Institute of Medical Sciences Rishikesh (IN)
Publication Details
- Journal
- BMJ Case Reports
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1136/bcr-2026-272000
- Primary Topic
- Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00