Novel insights into the imaging of axial spondyloarthritis

Axial spondyloarthritis (axSpA) is a chronic immune-mediated disease primarily affecting the sacroiliac joints and spine.Imaging plays a central role in the diagnosis, classification, and disease monitoring of axSpA.In this manuscript, recent developments in imaging that enhance both early detection and the understanding of disease progression are presented and discussed.Key topics include the role of conventional radiographs and their accuracy in the identification of axSpA-related imaging findings, the role of magnetic resonance imaging (MRI) scans or other advanced imaging techniques in identifying inflammatory and structural lesions, and the significance of fat lesions as a marker of postinflammatory changes with the potential to predict new bone formation.Emerging applications of quantitative imaging and artificial intelligence in image analysis are also highlighted.Recent advances in imaging have significantly transformed the diagnostic landscape of axSpA.These insights support the integration of imaging as a biomarker for personalised treatment strategies.

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Publication Details

Journal
EULAR Rheumatology Open
Published
2026-04-01
DOI
https://doi.org/10.1016/j.ero.2026.01.013
Primary Topic
Spondyloarthritis Studies and Treatments
Type
article
Field-Weighted Citation Impact
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article

Novel insights into the imaging of axial spondyloarthritis

Brikena Lalazi, Xenofon Baraliakos
EULAR Rheumatology Open
Spondyloarthritis Studies and Treatments
article

Novel insights into the imaging of axial spondyloarthritis

Brikena Lalazi, Xenofon Baraliakos
article en

Abstract

Axial spondyloarthritis (axSpA) is a chronic immune-mediated disease primarily affecting the sacroiliac joints and spine.Imaging plays a central role in the diagnosis, classification, and disease monitoring of axSpA.In this manuscript, recent developments in imaging that enhance both early detection and the understanding of disease progression are presented and discussed.Key topics include the role of conventional radiographs and their accuracy in the identification of axSpA-related imaging findings, the role of magnetic resonance imaging (MRI) scans or other advanced imaging techniques in identifying inflammatory and structural lesions, and the significance of fat lesions as a marker of postinflammatory changes with the potential to predict new bone formation.Emerging applications of quantitative imaging and artificial intelligence in image analysis are also highlighted.Recent advances in imaging have significantly transformed the diagnostic landscape of axSpA.These insights support the integration of imaging as a biomarker for personalised treatment strategies.

EULAR Rheumatology Open
Rheumazentrum Ruhrgebiet (DE), Ruhr University Bochum (DE)
Zero hunger
Openalex Percentile: Top 37%
Spondyloarthritis Studies and Treatments
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Novel insights into the imaging of axial spondyloarthritis — Brikena Lalazi, Xenofon Baraliakos · EULAR Rheumatology Open (2026) | TGRS Research Map | TGRS