Microbial regulation of intestinal stem cell function: implications for alleviating intestinal injury of weaned piglets
This review highlights how gut microbiota regulates intestinal stem cell function. Weaning stress disrupts this balance, causing intestinal injury in piglets. However, targeted nutritional interventions can modulate the gut microbiota to restore ISC function and repair tissue damage. Understanding this microbe-ISC interaction provides new, effective strategies to improve gut health and alleviate weaning-induced injury in animals.
Authors
- Jiangchao Zhao (ORCID: https://orcid.org/0000-0002-2894-8560)
- Meimei Zhang (ORCID: https://orcid.org/0000-0001-7587-6507)
- Jianmin Chai
- Feilong Deng
- Bo Song
- Hui Jiang
- Ying Li
Institutions
- South China Agricultural University (CN)
- Foshan University (CN)
- Key Laboratory of Guangdong Province (CN)
Publication Details
- Journal
- npj Biofilms and Microbiomes
- Published
- 2026-04-03
- DOI
- https://doi.org/10.1038/s41522-026-00973-1
- Primary Topic
- Animal Nutrition and Physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China