Generalization of fear learning is shaped by inhibitory sensory processing in mice

receptors in the olfactory bulb caused mice to switch from generalizing fear in proportion to similarity to instead overgeneralizing fear to all odors equally. Learning-induced sensory plasticity thus plays a causal role in shaping fear generalization.

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Publication Details

Journal
Nature Communications
Published
2026-04-03
DOI
https://doi.org/10.1038/s41467-026-71356-5
Primary Topic
Olfactory and Sensory Function Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Generalization of fear learning is shaped by inhibitory sensory processing in mice

John P. McGann, Alper Kagan Bakir, Ankur Gaikwad, Natalia Efimova et al.
Nature Communications
Olfactory and Sensory Function Studies
article

Generalization of fear learning is shaped by inhibitory sensory processing in mice

John P. McGann, Alper Kagan Bakir, Ankur Gaikwad, Natalia Efimova, Michelle C. Rosenthal, Katharina L. L. Clark
article en

Abstract

receptors in the olfactory bulb caused mice to switch from generalizing fear in proportion to similarity to instead overgeneralizing fear to all odors equally. Learning-induced sensory plasticity thus plays a causal role in shaping fear generalization.

Nature Communications
Rutgers, The State University of New Jersey (US), Johnson University (US)
National Institutes of Health
Openalex Percentile: Top 22%
Olfactory and Sensory Function Studies
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