Comparison of Three Different Doses of Dexmedetomidine for Attenuation of the Pressor Response to Laryngoscopy and Intubation by Assessment of Haemodynamic Parameters and Plasma Catecholamine Levels Under Bi-spectral Index Guided Anaesthesia - A Rand

Objective: under bi-spectral index monitoring and plasma catecholamine assessment. Methods: prior to induction. A baseline sample of catecholamines was taken and study drug was infused over 10 minutes. Thereafter, standard anaesthesia induction followed and haemodynamic parameters were noted at designated time intervals. Another sample of catecholamines was drawn at 3 minutes after intubation. The primary outcome was to compare the change in heart rate and systolic blood pressure. Secondary outcomes included: change in catecholamine levels, sedation scores, propofol dose and adverse events. Results: =0.014) were observed. Conclusion: had no added advantage.