Activation-gated, T cell-restricted silencing of Dapk1 enhances Bacille Calmette-Guérin-elicited protective CD4+ memory
challenge. These findings highlight a strategy to selectively modulate intrinsic death pathways during immune priming for strengthening vaccine-elicited T cell memory.
Authors
- Xuanchang Bai
- Fangting Zhou (ORCID: https://orcid.org/0000-0003-2984-7224)
- Pinru Chen (ORCID: https://orcid.org/0000-0003-0092-4265)
- Weihuang Liu (ORCID: https://orcid.org/0000-0002-9532-7633)
- Chenyu Zhao (ORCID: https://orcid.org/0009-0007-9490-2062)
- Min Liu
- Qin Pan
- Jiahe Shi
- Hang Sun
- Zixuan Liu
Institutions
- Wuhan University (CN)
Publication Details
- Journal
- iScience
- Published
- 2026-04-03
- DOI
- https://doi.org/10.1016/j.isci.2026.115593
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Ministry of Science and Technology of the People's Republic of China