Post-COVID-19 diabetes outcomes

Long-COVID-19 presentation has not been evaluated with proper depth in patients with diabetes (DM). This retrospective study evaluated 870 patients (320 DM, 550 non-DM) followed for up to 7.1 months post-hospitalization. Acute myocardial infarction, angina, articular edema, diarrhea, myocarditis/pericarditis were more frequent in patients with DM during the follow-up (p < 0.05). Recovery from COVID-19 symptoms was negatively associated with (89.8 × 94.27%; p = 0.038) while diarrhea, articular edema, abdominal pain, cardiovascular complications and worse health status were positively associated with DM. Patients with DM also had more frequent falls (21.1% × 11.1%; p = 0.0002033) and an increase in frailty scale score after COVID-19 (median of difference: 1 × 0; p = 6.124 × 10− 06). The quality of life of patients with diabetes was poorer with more frequent impaired mobility, inability to perform daily activity, discomfort and performed worse in physical and cognitive domains by WHODAS. Forty cases (7.3% of patients) of apparent new-onset diabetes were observed. Diabetes status did not affect the frequency of pain, skin problems, infections, newly diagnosed hypertension, abnormal lung sounds, post-COVID-19 hospital visit, anxiety and depression. Our data suggests a poorer outcome in diabetic patients and a 7.3% risk of diabetes progression in non-diabetic individuals up to 7.1 months after acute COVID-19.

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Publication Details

Journal
Scientific Reports
Published
2026-04-03
DOI
https://doi.org/10.1038/s41598-026-42284-7
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
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article

Post-COVID-19 diabetes outcomes

L. I. Alves, Adriana Aparecida Rosa, Maria Elizabeth Rossi da Silva, Adriana Bosco et al.
Scientific Reports
Long-Term Effects of COVID-19
article

Post-COVID-19 diabetes outcomes

L. I. Alves, Adriana Aparecida Rosa, Maria Elizabeth Rossi da Silva, Adriana Bosco, Chin Jia Lin
article en

Abstract

Long-COVID-19 presentation has not been evaluated with proper depth in patients with diabetes (DM). This retrospective study evaluated 870 patients (320 DM, 550 non-DM) followed for up to 7.1 months post-hospitalization. Acute myocardial infarction, angina, articular edema, diarrhea, myocarditis/pericarditis were more frequent in patients with DM during the follow-up (p < 0.05). Recovery from COVID-19 symptoms was negatively associated with (89.8 × 94.27%; p = 0.038) while diarrhea, articular edema, abdominal pain, cardiovascular complications and worse health status were positively associated with DM. Patients with DM also had more frequent falls (21.1% × 11.1%; p = 0.0002033) and an increase in frailty scale score after COVID-19 (median of difference: 1 × 0; p = 6.124 × 10− 06). The quality of life of patients with diabetes was poorer with more frequent impaired mobility, inability to perform daily activity, discomfort and performed worse in physical and cognitive domains by WHODAS. Forty cases (7.3% of patients) of apparent new-onset diabetes were observed. Diabetes status did not affect the frequency of pain, skin problems, infections, newly diagnosed hypertension, abnormal lung sounds, post-COVID-19 hospital visit, anxiety and depression. Our data suggests a poorer outcome in diabetic patients and a 7.3% risk of diabetes progression in non-diabetic individuals up to 7.1 months after acute COVID-19.

Scientific Reports
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Fundação de Amparo à Pesquisa do Estado de São Paulo, Faculdade de Medicina da Universidade de São Paulo
No poverty
Openalex Percentile: Top 8%
Long-Term Effects of COVID-19
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