Mild Oculocutaneous Albinism Type 1B With Subtle Cutaneous Findings: A Dermatology-Oriented Case Report

variants consistent with OCA1B, followed by genetic counseling regarding autosomal recessive inheritance. Dermatologic evaluation later revealed Fitzpatrick phototype II skin and gray-green irides consistent with a mild hypopigmented phenotype of OCA1B. Mild acneiform lesions were also observed and considered incidental findings. This case highlights the importance of dermatologic assessment within a multidisciplinary diagnostic pathway, contributing to the recognition of subtle cutaneous phenotypes and the implementation of long-term photoprotection and surveillance strategies in patients with mild albinism.

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Journal
Cureus
Published
2026-04-03
DOI
https://doi.org/10.7759/cureus.106375
Primary Topic
melanin and skin pigmentation
Type
article
Field-Weighted Citation Impact
0.00
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article

Mild Oculocutaneous Albinism Type 1B With Subtle Cutaneous Findings: A Dermatology-Oriented Case Report

Catalina Montané, Diego F. M. Guarda, Priscilla Márquez, Gerardo Bascuñán
Cureus
melanin and skin pigmentation
article

Mild Oculocutaneous Albinism Type 1B With Subtle Cutaneous Findings: A Dermatology-Oriented Case Report

Catalina Montané, Diego F. M. Guarda, Priscilla Márquez, Gerardo Bascuñán
article en

Abstract

variants consistent with OCA1B, followed by genetic counseling regarding autosomal recessive inheritance. Dermatologic evaluation later revealed Fitzpatrick phototype II skin and gray-green irides consistent with a mild hypopigmented phenotype of OCA1B. Mild acneiform lesions were also observed and considered incidental findings. This case highlights the importance of dermatologic assessment within a multidisciplinary diagnostic pathway, contributing to the recognition of subtle cutaneous phenotypes and the implementation of long-term photoprotection and surveillance strategies in patients with mild albinism.

CureusVol. 18(4)
Universidad de Santiago de Chile (CL), Puerto Rico Department of Health (PR), Universidad Andrés Bello (CL), Universidad Nacional del Comahue (AR)
Good health and well-being
Openalex Percentile: Top 34%
melanin and skin pigmentation
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