Breaking Barriers: Reducing Costs and Overcoming Challenges in <i>BCR::ABL-1</i> Monitoring for Chronic Myeloid Leukemia in Brazil

PURPOSE: test in a tertiary academic reference care center in Brazil and simulated alternatives to increase patient access to the test. METHODS: This is an economic analysis that estimates the costs based on resource consumption from a hospital to deliver a specific health care service, following the steps of the time-driven activity-based costing method at an academic reference center in Brazil. With the costs per test calculated, a scenario analysis estimated the budget impact resulting from an increase in test volume and a decrease in kit purchase cost, considering the local incidence of the disease. RESULTS: The cost per test was R$717, and if only laboratory reagents and personnel were considered, delivering the test to one patient accounted for R$556, whereas the current reimbursement fee is R$144. The simulated scenarios indicate that by increasing the volume of tests delivered by 60% and renegotiating the acquisition cost with the supplier in the same proportion, it is possible to cover 63% of the regional demand without increasing the budget impact. CONCLUSION: test with financial accountability.

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Publication Details

Journal
JCO Global Oncology
Published
2026-04-01
DOI
https://doi.org/10.1200/go-25-00724
Primary Topic
Chronic Myeloid Leukemia Treatments
Type
article
Field-Weighted Citation Impact
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article

Breaking Barriers: Reducing Costs and Overcoming Challenges in BCR::ABL-1 Monitoring for Chronic Myeloid Leukemia in Brazil

Ana Paula Beck da Silva Etges, Carísi Anne Polanczyk, Cláudia Cáceres Astigarraga, Caroline Dalla Pozza et al.
JCO Global Oncology
Chronic Myeloid Leukemia Treatments
article

Breaking Barriers: Reducing Costs and Overcoming Challenges in BCR::ABL-1 Monitoring for Chronic Myeloid Leukemia in Brazil

Ana Paula Beck da Silva Etges, Carísi Anne Polanczyk, Cláudia Cáceres Astigarraga, Caroline Dalla Pozza, Patricia Ashton-Prolla, Emanuela Pires
article en

Abstract

PURPOSE: test in a tertiary academic reference care center in Brazil and simulated alternatives to increase patient access to the test. METHODS: This is an economic analysis that estimates the costs based on resource consumption from a hospital to deliver a specific health care service, following the steps of the time-driven activity-based costing method at an academic reference center in Brazil. With the costs per test calculated, a scenario analysis estimated the budget impact resulting from an increase in test volume and a decrease in kit purchase cost, considering the local incidence of the disease. RESULTS: The cost per test was R$717, and if only laboratory reagents and personnel were considered, delivering the test to one patient accounted for R$556, whereas the current reimbursement fee is R$144. The simulated scenarios indicate that by increasing the volume of tests delivered by 60% and renegotiating the acquisition cost with the supplier in the same proportion, it is possible to cover 63% of the regional demand without increasing the budget impact. CONCLUSION: test with financial accountability.

JCO Global OncologyVol. 12(4)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR), Universidade Federal do Rio Grande do Sul (BR), Hospital de Clínicas de Porto Alegre (BR)
Openalex Percentile: Top 29%
Chronic Myeloid Leukemia Treatments
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