Phosphorylation of PfiA modulates Pf4 phage production through PfiA/PfiT stoichiometric reconfiguration in <i>Pseudomonas aeruginosa</i>
biofilm development. This study uncovers the cross-talk of TA systems from two coresident prophages and the role of posttranslational modification of TA system in mediating phage-phage and phage-host dynamics.
Authors
- Shituan Lin
- Ran Chen
- Jiayu Gu
- Yu Zhang
Institutions
- Jinan University (CN)
- Chinese Academy of Sciences (CN)
- Institute of Oceanology (CN)
- South China Sea Institute Of Oceanology (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Science Advances
- Published
- 2026-04-03
- DOI
- https://doi.org/10.1126/sciadv.aeb5480
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- National Natural Science Foundation of China
- Chinese Academy of Sciences
- South China Sea Institute of Oceanology, Chinese Academy of Sciences
- Institute of Oceanology, Chinese Academy of Sciences