Colostral fat content modulates glucose homeostasis and lipid metabolism in neonatal calves exposed to cold temperature

], total protein [TP], and IgG). Plasma GLU concentration increased during the first days after parturition in both LF and FF, with greater concentrations in FF during the first 4 d p.p. Serum concentrations of TG, TC, HDL-C, and VLDL-C were greater in FF until d 4 p.p., and TC and LDL-C were greater in FF compared with LF from d 5 to 21. No differences were observed for serum IgG, insulin, NEFA, and TP. Cortisol and glucagon concentrations as well as activity of GGT were elevated in LF compared with FF until d 4 of age. In conclusion, the present study showed that the fat content of colostrum and transition milk affected metabolic adaptation in neonatal calves during the first days of life. The overall lower energy availability in LF was reflected by changes of parameters related to glucose and lipid metabolism. Further studies investigating the impact of colostral fat content under different environmental conditions are warranted.