Discovery of FLC-8 as the First Covalent FLT3 Inhibitor Targeting Cys807 for FLT3 Mutant Acute Myeloid Leukemia
Authors
- Zhi‐Hao Shi (ORCID: https://orcid.org/0000-0002-6827-9533)
- Zheng Wang (ORCID: https://orcid.org/0000-0003-4873-505X)
- Jiao Cai
- Xiaolong Jing (ORCID: https://orcid.org/0009-0006-6665-9678)
- Meng-Yuan Zhang
- Qian Liu
- Qing-Qing Li
- Nian-Guang Li
- Tong Xian
Institutions
- Nanjing University of Chinese Medicine (CN)
- China Pharmaceutical University (CN)
Publication Details
- Journal
- Journal of Medicinal Chemistry
- Published
- 2026-04-03
- DOI
- https://doi.org/10.1021/acs.jmedchem.6c00511
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00