Mechanical Prophylaxis Management of Venous Thromboembolism in a General Surgical Setting: A Retrospective Cohort Study

Background and Aims: Patients undergoing pancreatectomy and hepatectomy are at high risk of venous thromboembolism (VTE) and bleeding. Mechanical prophylaxis effectively prevents VTE, yet optimal management strategies remain debated. This study compared two mechanical prophylaxis regimens in these surgical populations. Methods: = 627). Univariate analysis (chi-square test) and multivariate logistic regression were performed to assess hospital-associated VTE (HA-VTE) outcomes. Results: = 0.002). Conclusions: The ASPE regimen improved compliance with VTE prevention protocols. Postoperative mechanical prophylaxis significantly reduced HA-VTE incidence, supporting its clinical adoption.