Engineering the efficient Exo‐Cas12i2 for MITE manipulation in rice
Exo-Cas12i2 v1, a fusion of the 5' exonucleases T5E and PapE, facilitates editing of TA-rich regions and mediates deletions of large genomic fragments. Exo-Cas12i2 v1-driven MITE manipulation enables precise regulation of genes involved in gibberellin-mediated cell elongation and root ethylene responses to generate favorable agronomic traits.
Authors
- Jiantao Tan (ORCID: https://orcid.org/0000-0002-2240-1716)
- Nan Chai (ORCID: https://orcid.org/0000-0002-9155-8960)
- Kangli Sun (ORCID: https://orcid.org/0000-0002-6332-6660)
- Qinlong Zhu (ORCID: https://orcid.org/0000-0001-7622-6450)
- Xianrong Xie (ORCID: https://orcid.org/0000-0002-1438-7766)
- Yao‐Guang Liu
- Qian Qian
Institutions
- South China Agricultural University (CN)
- Rice Research Institute (CN)
- Guangdong Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Journal of Integrative Plant Biology
- Published
- 2026-04-02
- DOI
- https://doi.org/10.1111/jipb.70254
- Primary Topic
- Microfluidic and Capillary Electrophoresis Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00