A conversational multi-agent AI system for automated plant phenotyping
Plant phenotyping increasingly relies on (semi-)automated image-based analysis workflows to improve its accuracy and scalability. However, many existing solutions remain overly complex, difficult to reimplement and maintain, and pose high barriers for users without substantial computational expertise. To address these challenges, we introduce PhenoAssistant: a pioneering AI-driven system that streamlines plant phenotyping via intuitive natural language interaction. PhenoAssistant leverages a large language model to orchestrate a curated toolkit supporting tasks including automated phenotype extraction, data visualisation and automated model training. We validate PhenoAssistant through several representative case studies and a set of evaluation tasks. By lowering technical hurdles, PhenoAssistant underscores the promise of AI-driven methodologies to democratising AI adoption in plant biology.
Authors
- Jonathan A. Atkinson (ORCID: https://orcid.org/0000-0003-2815-0812)
- Malcolm John Hawkesford (ORCID: https://orcid.org/0000-0001-8759-3969)
- Mario Valerio Giuffrida (ORCID: https://orcid.org/0000-0002-5232-677X)
- Fraser Macfarlane (ORCID: https://orcid.org/0000-0002-7411-1446)
- Tony Pridmore (ORCID: https://orcid.org/0000-0002-9485-1978)
- Sotirios Tsaftaris
- Tracy Lawson (ORCID: https://orcid.org/0000-0002-4073-7221)
- Bruce Grieve (ORCID: https://orcid.org/0000-0002-5130-3592)
- Darren M. Wells (ORCID: https://orcid.org/0000-0002-4246-4909)
- Ilias Stogiannidis (ORCID: https://orcid.org/0009-0005-5803-1138)
- Danilo Bueno
- Stephen A. Rolfe
- Andrew Wood
- Feng Chen
- Dominic Williams
Institutions
- University of Essex (GB)
- University of Nottingham (GB)
- James Hutton Institute (GB)
- University of Illinois Urbana-Champaign (US)
- Rothamsted Research (GB)
- Dignity Health (US)
- University of Manchester (GB)
- Carnegie Department of Plant Biology (US)
- University of Sheffield (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Nature Communications
- Published
- 2026-04-03
- DOI
- https://doi.org/10.1038/s41467-026-71090-y
- Primary Topic
- Smart Agriculture and AI
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- UK Research and Innovation
- Directorate for Biological Sciences
- Engineering and Physical Sciences Research Council
- Biotechnology and Biological Sciences Research Council