High-Precision Synchronous Detection of Breath CO, CH <sub>4</sub> , and CO <sub>2</sub> Using an NIR-WMS Sensor Based on a Dual-Channel Multipass Cell

, as determined by Allan deviation analysis. The system was successfully deployed in breath testing, effectively distinguishing end-tidal CO levels between smokers and nonsmokers, with concentration trends consistent with those in the established literature. This work validates a reliable and practical TDLAS sensor for real-time, multicomponent breath analysis, offering a viable pathway toward noninvasive, high-sensitivity diagnostic devices.

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Publication Details

Journal
Analytical Chemistry
Published
2026-04-02
DOI
https://doi.org/10.1021/acs.analchem.5c08129
Primary Topic
Spectroscopy and Laser Applications
Type
article
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article

High-Precision Synchronous Detection of Breath CO, CH 4 , and CO 2 Using an NIR-WMS Sensor Based on a Dual-Channel Multipass Cell

Zhaoyue Huang, Hongyan Dong, Xue Ou, Yiyun Gai et al.
Analytical Chemistry
Spectroscopy and Laser Applications
article

High-Precision Synchronous Detection of Breath CO, CH 4 , and CO 2 Using an NIR-WMS Sensor Based on a Dual-Channel Multipass Cell

Zhaoyue Huang, Hongyan Dong, Xue Ou, Yiyun Gai, Guotao Zhang, Peng Liu
article en

Abstract

, as determined by Allan deviation analysis. The system was successfully deployed in breath testing, effectively distinguishing end-tidal CO levels between smokers and nonsmokers, with concentration trends consistent with those in the established literature. This work validates a reliable and practical TDLAS sensor for real-time, multicomponent breath analysis, offering a viable pathway toward noninvasive, high-sensitivity diagnostic devices.

Analytical ChemistryVol. 98(14)
Beijing Normal University (CN), Beijing Academy of Quantum Information Sciences (CN)
Openalex Percentile: Top 27%
Spectroscopy and Laser Applications
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