Comparative Efficacy and Safety of Fractional CO ₂ Laser and Gold Microneedling Radiofrequency for Atrophic Acne Scars: A Systematic Review

BACKGROUND: ) laser, have demonstrated significant potential in enhancing skin regeneration and improving the aesthetic appearance of acne scars. MATERIALS AND METHODS: laser creates precisely controlled microthermal zones that facilitate wound healing and promote the regeneration of new tissue. This review critically examines the clinical efficacy of these two modalities, exploring their individual mechanisms and comparing treatment outcomes. Additionally, the potential synergistic effects of combining these technologies are discussed. RESULTS: laser have demonstrated clinical efficacy in treating acne scars. The treatment outcomes, however, may vary depending on patient-specific factors and treatment parameters. The combined use of these modalities is currently under investigation for its potential to enhance therapeutic effects. CONCLUSION: laser have proven to be effective in improving acne scars, with promising results in skin regeneration and scar appearance. Future research should focus on refining treatment protocols and exploring the synergistic effects of combining these approaches to optimize clinical outcomes.