Intracellular acid-base regulation mediates a trade-off between shell and somatic growth in a clam under ocean acidification
-ATPase (NKA) was synergistically upregulated, suggesting an evolved adaptive pathway. Dynamic energy budget (DEB) modeling, calibrated with experimental data, revealed that this cellular compensation carries a high energetic cost, leading to a significant reallocation of resources: Shell growth was maintained, but somatic growth was severely suppressed. These results elucidate a conserved cytoprotective mechanism that enables short-term tolerance of OA at a substantial somatic cost, redefining resilience to include energetic trade-offs.
Authors
- Jianguang Fang (ORCID: https://orcid.org/0000-0003-0119-6108)
- Yuze Mao
- Meirong Du
- Øivind Strand (ORCID: https://orcid.org/0000-0001-9594-5928)
- Jinghui Fang (ORCID: https://orcid.org/0000-0002-7137-7214)
- Weiwei Li
- Samuel P.S. Rastrick
- Yaping Gao
- Mingjun Yuan
- Weiwei Jiang
- Zengjie Jiang
- Dong mei Xu
Institutions
- Norwegian Institute of Marine Research (NO)
- Qingdao National Laboratory for Marine Science and Technology (CN)
- Chinese Academy of Fishery Sciences (CN)
Publication Details
- Journal
- iScience
- Published
- 2026-04-02
- DOI
- https://doi.org/10.1016/j.isci.2026.115574
- Primary Topic
- Ocean Acidification Effects and Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Norges Forskningsråd
- Ministry of Agriculture and Rural Affairs of the People's Republic of China
- Chinese Academy of Fishery Sciences
- Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery Sciences