Semiotics and clinical reasoning: Thoracic ultrasound as an epistemic mediator

Clinical medicine and philosophy of science have come closer together during the past 30 years, particularly in the area of diagnostic reasoning.I contributed to this intertwining thanks to my studies on abductive cognition [1][2][3][4][5].Even while the scientifi c side of medicine has been improved by developments in physiology, imaging, and artifi cial intelligence, the fi rst, direct interaction with a patient is still a very human cognitive act.It is still diffi cult to fi nd straightforward but eff ective conceptual tools that may combine traditional semiotics with contemporary technologies.Th is issue's article by Soldati and colleagues presents a relevant, philosophically sound suggestion to redefi ne the chest physical examination around three pillars rather than four [6].It does this by positioning thoracic ultrasonography, or "insonation", as an active cognitive partner at the core of clinical epistemology [7].Th e key points made by Soldati et al. are succinctly summarized in this editorial, along with their wider implications for respiratory medicine and clinical reasoning in general [7].Th e writers start by going over the fundamentals of clinical knowledge.Th ey remind us that diagnosis is a fallibilistic, iterative search for the optimal explanatory hypothesis rather than a deductive or merely inductive process by drawing on Peirce's pragmatic semiotics and abductive inference.Th e abductive framework is used to gather, analyze, and continually update signs and the concept of epistemic mediators, which I fi rst proposed in the late 1990s and early 2000s, is introduced and explicitly expanded upon in this cycle.Th ese are tools and artifacts that act as real cognitive actors mediating between the patient's body, the doctor's mind, and the environment.Bedside thoracic ultrasonography is a wonderful fi t for this job, according to Soldati et al. [7].It actively contributes to the abductive loop by producing new surprises that lead to new hypotheses; it magnifi es signs that are imperceptible to conventional examination, palpation, percussion, and auscultation; and it converts acoustic energy into visual evidence.Th e use of insonation as a semiotic device is demonstrated in a particularly elegant section.According to the authors, percussion and ultrasound are quite similar in that they both use acoustic waves, are bedside, inexpensive, and instantly interpretable.Th e structural and functional correlations of classic signs (Damoiseau-Ellis line, Grocco's triangle, Garland's triangle, lung point, abolished sliding, sonographic interstitial syndrome, bronchograms) are revealed by ultrasonography.In doing so, it does more than just take the place of percussion; it clarifi es, corrects, and occasionally makes earlier fi ndings obsolete.Th e CHEPHEUS project (CHEst PHysical Examination integrated with UltraSound), already in its second phase [8], operationalizes this vision by proposing a modern triad: visual inspection, auscultation integrated with ultrasound, and palpatory ultrasound evaluation.Th ree pillars are suffi cient; percussion is no longer required as a stand-alone pillar.Th e hermeneutic dimension is equally signifi cant.Th e study conventionally but skillfully combines Gadamer's fusion of horizons, Ginzburg's evidential paradigm, and Peircean abduction [7].Both the patient and the doctor contribute their own assumptions, which are transformed into a shared, more expansive diagnostic horizon by the iterative semiotic process mediated by ultrasound.Because ultrasonography functions as an active epistemic mediator rather than a passive scanner, serendipitous fi ndings -such as pleural thickenings found by accident during eff usion evaluationbecome clinically signifi cant.

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Journal
Multidisciplinary Respiratory Medicine
Published
2026-04-02
DOI
https://doi.org/10.5826/mrm.2026.1099
Primary Topic
Clinical Reasoning and Diagnostic Skills
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article
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article

Semiotics and clinical reasoning: Thoracic ultrasound as an epistemic mediator

Lorenzo Magnani
Multidisciplinary Respiratory Medicine
Clinical Reasoning and Diagnostic Skills
article

Semiotics and clinical reasoning: Thoracic ultrasound as an epistemic mediator

Lorenzo Magnani
article en

Abstract

Clinical medicine and philosophy of science have come closer together during the past 30 years, particularly in the area of diagnostic reasoning.I contributed to this intertwining thanks to my studies on abductive cognition [1][2][3][4][5].Even while the scientifi c side of medicine has been improved by developments in physiology, imaging, and artifi cial intelligence, the fi rst, direct interaction with a patient is still a very human cognitive act.It is still diffi cult to fi nd straightforward but eff ective conceptual tools that may combine traditional semiotics with contemporary technologies.Th is issue's article by Soldati and colleagues presents a relevant, philosophically sound suggestion to redefi ne the chest physical examination around three pillars rather than four [6].It does this by positioning thoracic ultrasonography, or "insonation", as an active cognitive partner at the core of clinical epistemology [7].Th e key points made by Soldati et al. are succinctly summarized in this editorial, along with their wider implications for respiratory medicine and clinical reasoning in general [7].Th e writers start by going over the fundamentals of clinical knowledge.Th ey remind us that diagnosis is a fallibilistic, iterative search for the optimal explanatory hypothesis rather than a deductive or merely inductive process by drawing on Peirce's pragmatic semiotics and abductive inference.Th e abductive framework is used to gather, analyze, and continually update signs and the concept of epistemic mediators, which I fi rst proposed in the late 1990s and early 2000s, is introduced and explicitly expanded upon in this cycle.Th ese are tools and artifacts that act as real cognitive actors mediating between the patient's body, the doctor's mind, and the environment.Bedside thoracic ultrasonography is a wonderful fi t for this job, according to Soldati et al. [7].It actively contributes to the abductive loop by producing new surprises that lead to new hypotheses; it magnifi es signs that are imperceptible to conventional examination, palpation, percussion, and auscultation; and it converts acoustic energy into visual evidence.Th e use of insonation as a semiotic device is demonstrated in a particularly elegant section.According to the authors, percussion and ultrasound are quite similar in that they both use acoustic waves, are bedside, inexpensive, and instantly interpretable.Th e structural and functional correlations of classic signs (Damoiseau-Ellis line, Grocco's triangle, Garland's triangle, lung point, abolished sliding, sonographic interstitial syndrome, bronchograms) are revealed by ultrasonography.In doing so, it does more than just take the place of percussion; it clarifi es, corrects, and occasionally makes earlier fi ndings obsolete.Th e CHEPHEUS project (CHEst PHysical Examination integrated with UltraSound), already in its second phase [8], operationalizes this vision by proposing a modern triad: visual inspection, auscultation integrated with ultrasound, and palpatory ultrasound evaluation.Th ree pillars are suffi cient; percussion is no longer required as a stand-alone pillar.Th e hermeneutic dimension is equally signifi cant.Th e study conventionally but skillfully combines Gadamer's fusion of horizons, Ginzburg's evidential paradigm, and Peircean abduction [7].Both the patient and the doctor contribute their own assumptions, which are transformed into a shared, more expansive diagnostic horizon by the iterative semiotic process mediated by ultrasound.Because ultrasonography functions as an active epistemic mediator rather than a passive scanner, serendipitous fi ndings -such as pleural thickenings found by accident during eff usion evaluationbecome clinically signifi cant.

Multidisciplinary Respiratory MedicineVol. 21(Vol. 21 (2026))
University of Pavia (IT)
Quality Education
Openalex Percentile: Top 36%
Clinical Reasoning and Diagnostic Skills
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