Vitreous Opacities and Polyneuropathy in a 38-Year-Old Woman

A 38-year-old woman presented with eye heaviness and mild blurred vision without pain, illness, or trauma and a history of chronic inflammatory demyelinating polyneuropathy, unintentional weight loss, and gastrointestinal symptoms. Examination revealed bilateral vitreo-arterial tufts and scattered vitreous hyper-reflective signal accumulations. What would you do next?

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Publication Details

Journal
JAMA Ophthalmology
Published
2026-04-02
DOI
https://doi.org/10.1001/jamaophthalmol.2026.0539
Primary Topic
CNS Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Vitreous Opacities and Polyneuropathy in a 38-Year-Old Woman

Danny Varghese, Jake Young, Joseph Zimmer
JAMA Ophthalmology
CNS Lymphoma Diagnosis and Treatment
article

Vitreous Opacities and Polyneuropathy in a 38-Year-Old Woman

Danny Varghese, Jake Young, Joseph Zimmer
article en

Abstract

A 38-year-old woman presented with eye heaviness and mild blurred vision without pain, illness, or trauma and a history of chronic inflammatory demyelinating polyneuropathy, unintentional weight loss, and gastrointestinal symptoms. Examination revealed bilateral vitreo-arterial tufts and scattered vitreous hyper-reflective signal accumulations. What would you do next?

JAMA Ophthalmology
University of Arkansas – Fort Smith (US), Eye Center (SA), Bryan College (US)
Gender equality
Openalex Percentile: Top 5%
CNS Lymphoma Diagnosis and Treatment
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