Cytoprotective Effects of Lipid Emulsion Against Bupivacaine-Induced Cytotoxicity in Human Rotator Cuff Fibroblasts
< 0.05). Cell proliferation and wound healing were suppressed by bupivacaine but restored by LE and NAC pretreatment. This study demonstrates bupivacaine-induced cytotoxicity in hRCFs and suggests that LE and NAC mitigate these effects by reducing oxidative stress and promoting cell survival and wound healing.
Authors
- Ra Jeong Kim
- Hyung Bin Park
Institutions
- Changwon National University (KR)
- Gyeongsang National University (KR)
Publication Details
- Journal
- Antioxidants
- Published
- 2026-04-02
- DOI
- https://doi.org/10.3390/antiox15040447
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation of Korea