Fluorescent-Tagged, pH- and Redox-Responsive Polymeric Nanocarrier for Site-Specific Gastrointestinal Delivery
), ensuring stability in dilute environments. Spherical nanocarriers remain stable under acidic conditions (∼pH 2.0) and disassemble at neutral to basic pH (∼pH 7.4), mimicking gastrointestinal conditions. This property allows site-specific, stimulus-triggered drug release, with high drug-loading efficiency. The stimuli-responsiveness of the nanocarrier not only enhances oral drug delivery but also offers a versatile platform for encapsulating a wide range of therapeutics and diagnostics. This multifunctional nanocarrier system opens new avenues for personalized medicine and advanced material technologies, highlighting its potential for broader translational and industrial applications.
Authors
- Swarup Maity (ORCID: https://orcid.org/0009-0003-1599-4095)
- Sandipan Ghosh
- Sanjay Kumar Gupta
- Sudipta Paul
Institutions
- Indian Institute of Technology Bhilai (IN)
Publication Details
- Journal
- ACS Applied Materials & Interfaces
- Published
- 2026-04-02
- DOI
- https://doi.org/10.1021/acsami.6c01788
- Primary Topic
- Hydrogels: synthesis, properties, applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Biotechnology, Ministry of Science and Technology, India