Fluorescent-Tagged, pH- and Redox-Responsive Polymeric Nanocarrier for Site-Specific Gastrointestinal Delivery

), ensuring stability in dilute environments. Spherical nanocarriers remain stable under acidic conditions (∼pH 2.0) and disassemble at neutral to basic pH (∼pH 7.4), mimicking gastrointestinal conditions. This property allows site-specific, stimulus-triggered drug release, with high drug-loading efficiency. The stimuli-responsiveness of the nanocarrier not only enhances oral drug delivery but also offers a versatile platform for encapsulating a wide range of therapeutics and diagnostics. This multifunctional nanocarrier system opens new avenues for personalized medicine and advanced material technologies, highlighting its potential for broader translational and industrial applications.

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Publication Details

Journal
ACS Applied Materials & Interfaces
Published
2026-04-02
DOI
https://doi.org/10.1021/acsami.6c01788
Primary Topic
Hydrogels: synthesis, properties, applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Fluorescent-Tagged, pH- and Redox-Responsive Polymeric Nanocarrier for Site-Specific Gastrointestinal Delivery

Swarup Maity, Sandipan Ghosh, Sanjay Kumar Gupta, Sudipta Paul
ACS Applied Materials & Interfaces
Hydrogels: synthesis, properties, applications
article

Fluorescent-Tagged, pH- and Redox-Responsive Polymeric Nanocarrier for Site-Specific Gastrointestinal Delivery

Swarup Maity, Sandipan Ghosh, Sanjay Kumar Gupta, Sudipta Paul
article en

Abstract

), ensuring stability in dilute environments. Spherical nanocarriers remain stable under acidic conditions (∼pH 2.0) and disassemble at neutral to basic pH (∼pH 7.4), mimicking gastrointestinal conditions. This property allows site-specific, stimulus-triggered drug release, with high drug-loading efficiency. The stimuli-responsiveness of the nanocarrier not only enhances oral drug delivery but also offers a versatile platform for encapsulating a wide range of therapeutics and diagnostics. This multifunctional nanocarrier system opens new avenues for personalized medicine and advanced material technologies, highlighting its potential for broader translational and industrial applications.

ACS Applied Materials & InterfacesVol. 18(14)
Indian Institute of Technology Bhilai (IN)
Department of Biotechnology, Ministry of Science and Technology, India
Industry, innovation and infrastructure
Openalex Percentile: Top 32%
Hydrogels: synthesis, properties, applications
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