Gonadal Function and Fertility after Hodgkin Lymphoma Treatment with Nivolumab-AVD in the Phase II GHSG NIVAHL Trial
In 82 patients with classic Hodgkin lymphoma, stable gonadal hormone levels were observed up to 24 months after nivolumab and AVD (N-AVD) first-line treatment in the NIVAHL trial. These findings suggest preserved gonadal function and fertility following 4×N-AVD. NCT03004833.
Authors
- Peter Herhaus
- Christian Baues (ORCID: https://orcid.org/0000-0003-1733-6064)
- Andreas Dickhut
- Ina Bühnen
- Carsten Kobe (ORCID: https://orcid.org/0000-0002-2909-0826)
- Teresa Halbsguth
- Andrea Kerkhoff (ORCID: https://orcid.org/0000-0001-6904-2821)
- Stephan Mathas (ORCID: https://orcid.org/0000-0001-9626-1413)
- Christian Jaworek (ORCID: https://orcid.org/0009-0007-9338-2624)
- Matthias Bormann
- Michael Fuchs (ORCID: https://orcid.org/0000-0003-3289-3272)
- A. S. Robertz
- P Borchmann
- Bastian von Tresckow
- Karolin Trautmann-Grill
- Valdete Schaub
- Julia Meissner
- Paul J Bröckelmann
- Karolin Behringer
Institutions
- Goethe University Frankfurt (DE)
- Max Delbrück Center (DE)
- Heidelberg University (DE)
- University Hospitals of the Ruhr-University of Bochum (DE)
- TUM Klinikum (DE)
- Düsseldorf University Hospital (DE)
- Integrated Oncology (United States) (US)
- University Hospital Münster (DE)
- Essen University Hospital (DE)
- Hochschule für Gesundheit - University of Applied Sciences (DE)
- University Hospital Frankfurt (DE)
- STZ eyetrial (DE)
- Klinikum Bremen-Mitte (DE)
- University Hospital Cologne (DE)
- Klinikum Fulda (DE)
- West German Heart and Vascular Center Essen (DE)
- University Hospital Carl Gustav Carus (DE)
- Heinrich Heine University Düsseldorf (DE)
- Charité - Universitätsmedizin Berlin (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- Blood
- Published
- 2026-04-02
- DOI
- https://doi.org/10.1182/blood.2025031809
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00