Comparative Performance of Large Language Models on European Gastroenterology Board-Style Questions: Analysis of Reasoning Versus Non-Reasoning Architectures

: This benchmarking study demonstrates that current LLMs, particularly those with reasoning architectures, achieve high accuracy on European gastroenterology board-style questions. However, significant performance gaps in specific domains highlight limitations that must be addressed before clinical application. These findings provide a baseline for evaluating LLM capabilities in European medical contexts.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-02
DOI
https://doi.org/10.3390/jcm15072692
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparative Performance of Large Language Models on European Gastroenterology Board-Style Questions: Analysis of Reasoning Versus Non-Reasoning Architectures

Manuel Lehner, Cesare Hassan, Jan Krivinka, Petr Vaněk et al.
Journal of Clinical Medicine
Artificial Intelligence in Healthcare and Education
article

Comparative Performance of Large Language Models on European Gastroenterology Board-Style Questions: Analysis of Reasoning Versus Non-Reasoning Architectures

Manuel Lehner, Cesare Hassan, Jan Krivinka, Petr Vaněk, Hakan Aydinli, Henriette H. Heinrich, Sara Schiavone, Cem Simsek
article en

Abstract

: This benchmarking study demonstrates that current LLMs, particularly those with reasoning architectures, achieve high accuracy on European gastroenterology board-style questions. However, significant performance gaps in specific domains highlight limitations that must be addressed before clinical application. These findings provide a baseline for evaluating LLM capabilities in European medical contexts.

Journal of Clinical MedicineVol. 15(7)
University of Minnesota (US), Humanitas University (IT), University of Basel (CH), Masaryk University (CZ), University Hospital Brno (CZ), University Hospital Olomouc (CZ), Masaryk Memorial Cancer Institute (CZ), University of Minnesota Medical Center (US), IRCCS Humanitas Research Hospital (IT), Hacettepe University (TR), Palacký University Olomouc (CZ)
Openalex Percentile: Top 29%
Artificial Intelligence in Healthcare and Education
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Comparative Performance of Large Language Models on European Gastroenterology Board-Style Questions: Analysis of Reasoning Versus Non-Reasoning Architectures — Manuel Lehner, Cesare Hassan, et al. · Journal of Clinical Medicine (2026) | TGRS Research Map | TGRS