Hydrodynamic Delivery of IL-10 Gene for Local Immunomodulation in Human Crohn’s Disease Tissue: A Proof-of-Concept Study
: These findings establish arterial hydrodynamic delivery as a feasible, non-viral strategy for targeted gene therapy in IBD.
Authors
- Gladys G. Olivera (ORCID: https://orcid.org/0000-0002-7698-2122)
- Salvador F. Aliño (ORCID: https://orcid.org/0000-0002-7830-8713)
- Matteo Frasson (ORCID: https://orcid.org/0000-0002-4753-1832)
- Luis Sendra (ORCID: https://orcid.org/0000-0003-3176-9763)
- Enrique G. Zucchet
- Francisco Giner
- María José Herrero
Institutions
- Universitat de València (ES)
- Hospital Universitari i Politècnic La Fe (ES)
- Instituto de Investigación Sanitaria La Fe (ES)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2026-04-02
- DOI
- https://doi.org/10.3390/pharmaceutics18040442
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitat de València
- Instituto de Salud Carlos III