Asymmetric Total Synthesis and Structure Revision of (+)-Mangicol D
-mediated reductive cyclization to establish the spiro-fused tetracyclic framework in a concise manner. Our findings suggest a stereochemical revision of the polyol side chain of the initially isolated mangicols.
Authors
- Zhouyang Zhu (ORCID: https://orcid.org/0009-0001-1938-6586)
- Thomas J. Maimone (ORCID: https://orcid.org/0000-0001-5823-692X)
- Shang Ning (ORCID: https://orcid.org/0000-0002-3908-8754)
- Yutong Wang (ORCID: https://orcid.org/0000-0001-7796-7779)
- Yi Xie
Institutions
- University of California, Berkeley (US)
Publication Details
- Journal
- Journal of the American Chemical Society
- Published
- 2026-04-02
- DOI
- https://doi.org/10.1021/jacs.6c01185
- Primary Topic
- Natural Compound Pharmacology Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health