Copper-Catalyzed Decarboxylative Cascade Annulation of Propargylic Cyclic Carbamates with Allenediones

selectivity. A proposed mechanism indicated that the reaction undergoes a cascade [4+1] annulation/intramolecular cyclization reaction. This cascade process underscores the promising potential of copper-allenylidenes in the construction of complex fused ring systems through cascade annulation.

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Publication Details

Journal
Organic Letters
Published
2026-04-02
DOI
https://doi.org/10.1021/acs.orglett.6c00674
Primary Topic
Catalytic C–H Functionalization Methods
Type
article
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article

Copper-Catalyzed Decarboxylative Cascade Annulation of Propargylic Cyclic Carbamates with Allenediones

Bing Zheng, Mengxi Lu, Rongbin Li, J.P. Du et al.
Organic Letters
Catalytic C–H Functionalization Methods
article

Copper-Catalyzed Decarboxylative Cascade Annulation of Propargylic Cyclic Carbamates with Allenediones

Bing Zheng, Mengxi Lu, Rongbin Li, J.P. Du, J Tu, Hongchao Guo
article en

Abstract

selectivity. A proposed mechanism indicated that the reaction undergoes a cascade [4+1] annulation/intramolecular cyclization reaction. This cascade process underscores the promising potential of copper-allenylidenes in the construction of complex fused ring systems through cascade annulation.

Organic LettersVol. 28(15)
Nutricia Research (Netherlands) (NL), China Agricultural University (CN)
Clean water and sanitation
Openalex Percentile: Top 28%
Catalytic C–H Functionalization Methods
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