Pirfenidone Reduces Intracochlear Fibrosis Caused by Cochlear Implantation in a Guinea Pig Model
= 0.0436). Overall, these data demonstrate that PFD shows significant therapeutic potential in reducing cochlear implant-induced fibrosis.
Authors
- Tylah Miles
- Jafri Kuthubutheen (ORCID: https://orcid.org/0000-0003-2550-2472)
- Lee Yong Lim (ORCID: https://orcid.org/0000-0002-7307-0742)
- Cecilia M. Prêle (ORCID: https://orcid.org/0000-0002-9014-263X)
- Marcus D. Atlas (ORCID: https://orcid.org/0000-0001-9830-259X)
- Kady J. Braack (ORCID: https://orcid.org/0000-0003-1076-5843)
- Kelly L. Short
- Jorjina Plester
- Wilhelmina H. A. M. Mulders
Institutions
- Murdoch University (AU)
- The University of Western Australia (AU)
- Government of Western Australia Department of Health (AU)
- Sir Charles Gairdner Hospital (AU)
- Institute for Respiratory Health (AU)
- Ear Science Institute Australia (AU)
Publication Details
- Journal
- International Journal of Molecular Sciences
- Published
- 2026-04-02
- DOI
- https://doi.org/10.3390/ijms27073242
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Australian Government
- MED-EL Medical Electronics
- Medical Research Council
- National Health and Medical Research Council