Circulating extracellular vesicle microRNAs mediate immune modulation of social behavior in male mice
mice. These findings uncover the role of EV miRNAs in mediating immune modulation of synaptic function and social behavior, revealing a non-canonical molecular pathway for immune-neuron communication.
Authors
- Oluwaseun Fatoba (ORCID: https://orcid.org/0000-0002-9046-3943)
- Eisuke Dohi (ORCID: https://orcid.org/0000-0002-5365-4900)
- Indigo V.L. Rose (ORCID: https://orcid.org/0000-0003-0491-1269)
- Shin‐ichi Kano (ORCID: https://orcid.org/0000-0002-5171-3436)
- Takashi Imai (ORCID: https://orcid.org/0000-0001-9049-8102)
- Eric Y. Choi (ORCID: https://orcid.org/0000-0002-0023-6844)
- Inssaf Berkiks (ORCID: https://orcid.org/0000-0002-6825-5523)
- Norimichi Ito
- David K. Crossman (ORCID: https://orcid.org/0000-0002-0981-169X)
- Minae Niwa (ORCID: https://orcid.org/0000-0002-8784-7815)
- Jana Badrani
- Phoebe A. Garcia
- Takahiro Kochi (ORCID: https://orcid.org/0000-0003-0353-8300)
- Rei Mitani
- Frida Anguiano (ORCID: https://orcid.org/0009-0002-3558-8521)
- Ken Matoba
- Jose Francis-Oliveira
- Md. Sorwer Alam Parvez
- Julia See
- Mirmohammadali Mirramezanializamini
- Mikhail V. Pletnikov
- Kenneth W. Witwer
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- University of Alabama at Birmingham (US)
- Behavioral Pharma (United States) (US)
- National Center of Neurology and Psychiatry (JP)
- University at Buffalo, State University of New York (US)
Publication Details
- Journal
- Nature Communications
- Published
- 2026-04-03
- DOI
- https://doi.org/10.1038/s41467-026-70469-1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Paul G. Allen Family Foundation
- National Institute of Mental Health