FGF2 Deficiency Modulates Early Microglial Responses Without Affecting Photoreceptor Survival in a Retinitis Pigmentosa Mouse Model
controls, suggesting that FGF2 modulates inflammatory signaling. Together, these results show that loss of FGF2 does not alter photoreceptor degeneration kinetics or retinal morphology, but may contribute to the regulation of early microglial accumulation during degeneration.
Authors
- Susanne Koch (ORCID: https://orcid.org/0000-0001-9966-113X)
- Felia C. Haffelder
- Zeynep Okutan
- Nundehui Díaz-Lezama
- Claudia Grothe
Institutions
- Medizinische Hochschule Hannover (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Cells
- Published
- 2026-04-02
- DOI
- https://doi.org/10.3390/cells15070643
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Bayerische Forschungsstiftung