Cellular Processes and Forces Shaping the Embryo: Lessons from C. elegans

embryonic morphogenesis. Building on past reviews in the field, we analyze dorsal intercalation, ventral enclosure, and axis extension, with a focus on how forces impinge on cellular processes and serve to coordinate morphogenesis across adjacent tissues through mechanotransduction. We also discuss how different forms of cellular rosettes contribute to ventral patterning and head morphogenesis, which had not been discussed in previous reviews. Throughout, we highlight how the reciprocal feedback mechanisms between molecular processes and mechanical forces, as well as cell material properties, shape the embryo.

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Publication Details

Journal
Cells
Published
2026-04-02
DOI
https://doi.org/10.3390/cells15070645
Primary Topic
Cellular Mechanics and Interactions
Type
article
Field-Weighted Citation Impact
0.00

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article

Cellular Processes and Forces Shaping the Embryo: Lessons from C. elegans

Michel Labouesse, Zoe Tesone, Teresa Ferraro, Jeff Hardin et al.
Cells
Cellular Mechanics and Interactions
article

Cellular Processes and Forces Shaping the Embryo: Lessons from C. elegans

Michel Labouesse, Zoe Tesone, Teresa Ferraro, Jeff Hardin, Flora Llense, Jonathon Heier
article en

Abstract

embryonic morphogenesis. Building on past reviews in the field, we analyze dorsal intercalation, ventral enclosure, and axis extension, with a focus on how forces impinge on cellular processes and serve to coordinate morphogenesis across adjacent tissues through mechanotransduction. We also discuss how different forms of cellular rosettes contribute to ventral patterning and head morphogenesis, which had not been discussed in previous reviews. Throughout, we highlight how the reciprocal feedback mechanisms between molecular processes and mechanical forces, as well as cell material properties, shape the embryo.

CellsVol. 15(7)
University of Wisconsin–Madison (US), Sorbonne Université (FR), Institut de Biologie Paris-Seine (FR)
Agence Nationale de la Recherche, European Research Council
Openalex Percentile: Top 33%
Cellular Mechanics and Interactions
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