Electroreductive Cross-Coupling of Cyclopropyl Ketones and Aryl Methyl Ketones to Access 1,2,4-Triarylbenzenes via Acid-Promoted Aromatization
-hydroxy ketone intermediate that undergoes acid-promoted aromatization to afford 1,2,4-triarylbenzenes. This telescopic two-step synthetic strategy obviates the need for external oxidants or reductants and provides a broad substrate scope with remarkable functional group tolerance. Additionally, the practicality of the designed strategy was evidenced by its scalability and further derivatization of the synthesized triarylbenzenes.
Authors
- Prabal Banerjee (ORCID: https://orcid.org/0000-0002-3569-7624)
- Debarshi Saha (ORCID: https://orcid.org/0000-0001-7434-1981)
- R. Banerjee
- Rohan Bag
- Chandan Laru
Institutions
- Indian Institute of Technology Ropar (IN)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-04-02
- DOI
- https://doi.org/10.1021/acs.orglett.6c00754
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Science and Technology, Ministry of Science and Technology, India
- University Grants Commission
- Indian Institute of Technology Ropar
- Science and Engineering Research Board