MK2/p38/p53 Suppress Basal IL-1β and Non-Canonical NF-κB Signaling in Macrophages
expression. Additionally, they reveal a new mechanism that contributes to the long-discussed link between cancer and inflammation, wherein the tumor suppressor p53 inhibits cytokine production in parallel.
Authors
- Matthias Gaestel (ORCID: https://orcid.org/0000-0002-4944-4652)
- Natalia Ronkina (ORCID: https://orcid.org/0000-0001-6350-700X)
- L. Herbst
- Anneke Dörrie
- Rainer Niedenthal
- Diana Stalkopf
- Sofie Padaszus
- Sarah M. Herr
- Alexey Kotlyarov
- Tatiana Yakovleva
Institutions
- Medizinische Hochschule Hannover (DE)
Publication Details
- Journal
- International Journal of Molecular Sciences
- Published
- 2026-04-02
- DOI
- https://doi.org/10.3390/ijms27073232
- Primary Topic
- Melanoma and MAPK Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medizinischen Hochschule Hannover