Synergistic Potential of Organotin(IV) Carbodithioate Derivatives with Vitamins D and E in MCF-7 and MDA-MB-231 Breast Cancer Cells
: Collectively, these results identify Complex 4 as a promising lead compound, and its synergistic activity with natural vitamins may promote cell death, likely through apoptosis induction and modulation of oxidative stress, underscoring its potential as an effective and less toxic therapeutic strategy for breast cancer management.
Authors
- Farzana Shaheen (ORCID: https://orcid.org/0000-0003-0057-3960)
- Balquees Kanwal (ORCID: https://orcid.org/0000-0001-5464-3923)
- Yasmeen Cheema (ORCID: https://orcid.org/0009-0000-2791-1822)
- Syeda Saba Shah
- Rumeza Hanif (ORCID: https://orcid.org/0000-0003-4585-6382)
- Saqib Ali (ORCID: https://orcid.org/0000-0002-5397-7101)
Institutions
- Quaid-i-Azam University (PK)
- Allama Iqbal Open University (PK)
- National University of Sciences and Technology (PK)
Publication Details
- Journal
- Pharmaceuticals
- Published
- 2026-04-02
- DOI
- https://doi.org/10.3390/ph19040571
- Primary Topic
- Organometallic Compounds Synthesis and Characterization
- Type
- article
- Field-Weighted Citation Impact
- 0.00