Combined Biomarker Approach Using Extracellular Vesicles, Donor-Derived Cell-Free DNA, and Donor-Specific Antibodies for Monitoring Renal Allograft Function: A Narrative Review
The integration of EV, ddcfDNA, and DSA monitoring into a unified surveillance framework offers a clinically meaningful advance over creatinine-based monitoring. Prospective randomized trials confirming improvement in long-term allograft survival will be the critical next step.
Authors
- Henrik Birn (ORCID: https://orcid.org/0000-0003-3715-7266)
- Kumar Digvijay (ORCID: https://orcid.org/0000-0002-0906-1745)
Institutions
- Aarhus University Hospital (DK)
Publication Details
- Journal
- Medicina
- Published
- 2026-03-31
- DOI
- https://doi.org/10.3390/medicina62040664
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00