TAAR5 Modulates Sensorimotor Recovery After Spinal Cord Injury
: These findings indicate that TAAR5 deficiency exerts a positive modulatory effect on the restoration of specific components of sensorimotor function after SCI. This effect may be mediated through the modulation of dopaminergic neurotransmission and inflammatory processes. The observed beneficial effect of TAAR5 knockout identifies this receptor as a promising target for developing novel therapeutic strategies aimed at improving functional outcomes following spinal cord injury.
Authors
- Raul R. Gainetdinov (ORCID: https://orcid.org/0000-0003-2951-6038)
- Nataliia V. Katolikova (ORCID: https://orcid.org/0000-0002-7098-4864)
- Polina Shkorbatova (ORCID: https://orcid.org/0000-0001-5777-7775)
- P. Musienko
- Daria Kalinina
- Natalia Pavlova (ORCID: https://orcid.org/0000-0002-0661-6477)
- E. A. Romanyuk
- S. I. Milov
- A. A. Chesnokov
- Anastasiia D. Buglinina
Institutions
- St Petersburg University (RU)
- Sirius University of Science and Technology (RU)
- Pavlov Institute of Physiology of the Russian Academy of Sciences (RU)
- Centre of Advanced Studies (RU)
Publication Details
- Journal
- Biomedicines
- Published
- 2026-03-31
- DOI
- https://doi.org/10.3390/biomedicines14040796
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Saint Petersburg State University
- Russian Science Foundation
- Russian Academy of Sciences