Longitudinal Evaluation of <sup>18</sup> F-MK-6240 Along the Alzheimer Disease Continuum
F-MK-6240 PET tracked tau accumulation over time and provided preliminary evidence that these changes correlate with cognitive decline, supporting its utility for longitudinal AD studies and trial design, with MTC emerging as a promising ROI for clinical trials.
Authors
- Tobey J. Betthauser (ORCID: https://orcid.org/0000-0001-8856-1352)
- Robert V. Cadman (ORCID: https://orcid.org/0000-0001-7685-1977)
- Anna O. Giarratana (ORCID: https://orcid.org/0000-0002-6734-7901)
- Erin M. Jonaitis (ORCID: https://orcid.org/0009-0004-5091-8255)
- Karly Alex Cody (ORCID: https://orcid.org/0000-0001-5996-2560)
- Robert J. Przybelski
- Sara Frost Alberson
- Bradley T. Christian
- Sterling C. Johnson
Institutions
- University of Wisconsin–Madison (US)
- Wisconsin Division of Public Health (US)
Publication Details
- Journal
- Journal of Nuclear Medicine
- Published
- 2026-04-02
- DOI
- https://doi.org/10.2967/jnumed.125.271127
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00